Jan 28, - WebMD explores some little known things about male masturbation and answers But like other low-risk activities (chewing, walking), it still has some risks. Guys can get hung up on whether they masturbate too much. Dec 7, - Masturbation side effects. Masturbation is harmless. Some people may experience chafing or tender skin if they are too rough, but this will usually heal in a few days. If men frequently masturbate within a short space of time, they may experience a slight swelling of the penis called an edema.